A model for the rat exploratory behavior in the elevated plus-maze
نویسندگان
چکیده
منابع مشابه
Study the Effect of Endocannabinoid System on Rat Behavior in Elevated Plus-Maze
Introduction: Previous studies have shown that cannabinoidergic system is involved in anxiety. However, there are controversial reports in the experimental studies. The aim of this study is to evaluate the effect of pharmacological stimulation or blocking of CB1 receptors and inhibition of endocannabinoid degradation in anxiety like behavior in elevated plus-maze (EPM) test in rat. The EPM is o...
متن کاملVibrissal sense is not the main sensory modality in rat exploratory behavior in the elevated plus-maze.
Four groups of male Wistar rats were submitted to acute bilateral removal of mystacial vibrissae at different lengths from the follicle. Each group was divided into two subgroups, tested under high (150 Lux) and low environmental illumination (2 Lux). All the subjects were allowed to freely explore an elevated plus-maze for 5 min. Results indicated that rats tested under low illumination tended...
متن کاملstudy the effect of endocannabinoid system on rat behavior in elevated plus-maze
introduction: previous studies have shown that cannabinoidergic system is involved in anxiety. however, there are controversial reports in the experimental studies. the aim of this study is to evaluate the effect of pharmacological stimulation or blocking of cb1 receptors and inhibition of endocannabinoid degradation in anxiety like behavior in elevated plus-maze (epm) test in rat. the epm is o...
متن کاملModulation of Anxiety-Like Behavior in Sildenafil Citrate-Treated Mice Placed in an Elevated Plus-Maze
Introduction: Sildenafil, a phosphodiesterase-5 (PDE5) inhibitor, may have various effects on the central nervous system via the nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) pathway. Preclinical studies have shown the controversial effect of sildenafil on anxiety-like behavior in animals. This study was undertaken to investigate the acute effect of sildenafil on anxiety-like behavior...
متن کاملEffects of under- and overcrowding on exploratory behavior in the elevated plus-maze.
The present work investigated whether the number of rats housed in a cage affects exploration of an elevated plus-maze. Male Wistar-derived rats were kept 1, 2, 3, 4, 6, 8, 12, 16, or 24 to same size cages either for 1 or 14 days and tested in the elevated plus-maze. Rats kept 6 to a cage were arbitrarily considered controls because this is the housing condition adopted in many laboratories, ou...
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ژورنال
عنوان ژورنال: BMC Neuroscience
سال: 2007
ISSN: 1471-2202
DOI: 10.1186/1471-2202-8-s2-p37